Zar Chi Soe

As a teaching staff in the University of Pharmacy, I dedicated, knowledgeable, and dynamic group of professionals committed to excellence in education, research, and community engagement. The students are well-prepared to meet the demands of the evolving pharmaceutical landscape and to contribute meaningfully to public health and scientific advancement.

As a postdoctoral researcher, I conducted with a robust background in nanotechnology development in cellular study. Demonstrated expertise in conducting innovative research, and developing experimental designs. Experienced in mentoring graduate and undergraduate students.

• Member, Myanmar Pharmaceutical Association
• Member, Factory Council of Traditional Medicine
• Member, Myanmar Maternal and Child Welfare Association
• Member, Myanmar Woman Enterprise Association

• Pharmaceutical Science
• Pharmacology
• Nanotechnology
• Stem cells and cancer cells therapy
• Pharmacy Practice

• Yeungnam University, Department of Pharmacy, Pharmaceutical Sciences Department, Gyeongsan, Republic of Korea, 03/2016, 02/2019, Dr. Chul Soon Yong, Dr. Jong Oh Kim, Lipid Nanoparticle synthesis and delivery, Pre-formulation studies, Dynamic Light scattering (DLS), Transmission Electron Microscopes (TEM), Scanning Electron Microscopes (SEM), Cryo-EM, HPLC, Differential scanning calorimetry (DSC), X-ray powder diffraction (XRD), Atomic force microscopy (AFM), Release study, Confocal Microscopy, Fluorescence Microscope, Immunohistochemistry, Gel Electrophoresis, Real-time polymerase chain reaction (RT-PCR), Enzyme-linked immunosorbent Assay, Western Blotting, Cell Culture Preparation, Cytotoxicity assays, Live and Dead assay, Flow cytometry, Cell Cycle Assay Cell-Clock, Cell migration assay, Reactive oxygen species production (ROS) assay, Mice handling and general in vivo experiments, In-vivo imaging system (IVIS), Xenograft tumor model development, Independently designed, developed project plans, and conducted formulation projects on lipid/polymer-based nanoparticles (liposome, and other organic and inorganic nanoparticles), Trained to perform cell culture in different cancer and other cell lines, Skilled in handling different instruments (Light microscopy, fluorescence microscopy, confocal microscopy, PCR, FACS, IVIS, HPLC, UV, FT-IR, DSC, XRD, SEM, TEM, AFM, Zeta sizer, DLS scattering, and Dissolution apparatus), Performed different studies: Western blot, MTT/MTS assay, Live and Dead assay, FACS apoptosis, Hoechst staining, Intracellular uptake study, Cell Cycle Assay Cell-Clock, Cell migration, RNA extraction, PCR and ELISA etc., Learned animal handling techniques, developed xenograft different tumour models in Balc/c, Balc/c nude, and performed all the tumour-related studies (bodyweight monitoring, tumour volume measurement, survival study, measurement of tumour weight after mice sacrifice), along with their statistical analysis, Skilled in developing in-vivo skin infection models by using bacterial strains, and performed in-vivo antibacterial and in-vivo toxicity studies
• Postdoctoral researcher, Department of Oral Biology, Faculty of Dental, Chulalongkorn University, Thailand, 06/2023, current, Lipid Nanoparticle synthesis and delivery, Pre-formulation studies, Dynamic Light scattering (DLS), Transmission Electron Microscopes (TEM), Scanning Electron Microscopes (SEM), Cryo-EM, HPLC, Differential scanning calorimetry (DSC), X-ray powder diffraction (XRD), Atomic force microscopy (AFM), Release study, Confocal Microscopy, Fluorescence Microscope, Immunohistochemistry, Gel Electrophoresis, Real-time polymerase chain reaction (RT-PCR), Enzyme-linked immunosorbent Assay, Western Blotting, Cell Culture Preparation, Cytotoxicity assays, Live and Dead assay, Flow cytometry, Cell Cycle Assay Cell-Clock, Cell migration assay, Reactive oxygen species production (ROS) assay, Mice handling and general in vivo experiments, In-vivo imaging system (IVIS), Xenograft tumor model development, Independently designed, developed project plans, and conducted formulation projects on lipid/polymer-based nanoparticles (liposome, and other organic and inorganic nanoparticles), Trained to perform cell culture in different cancer and other cell lines, Skilled in handling different instruments (Light microscopy, fluorescence microscopy, confocal microscopy, PCR, FACS, IVIS, HPLC, UV, FT-IR, DSC, XRD, SEM, TEM, AFM, Zeta sizer, DLS scattering, and Dissolution apparatus), Performed different studies: Western blot, MTT/MTS assay, Live and Dead assay, FACS apoptosis, Hoechst staining, Intracellular uptake study, Cell Cycle Assay Cell-Clock, Cell migration, RNA extraction, PCR and ELISA etc., Learned animal handling techniques, developed xenograft different tumour models in Balc/c, Balc/c nude, and performed all the tumour-related studies (bodyweight monitoring, tumour volume measurement, survival study, measurement of tumour weight after mice sacrifice), along with their statistical analysis, Skilled in developing in-vivo skin infection models by using bacterial strains, and performed in-vivo antibacterial and in-vivo toxicity studies

• Total Teaching Service year is 18 and half years at the University of Pharmacy.
• Regular classes covering various subjects, pharmaceutics, Pharmaceutical microbiology and Pharmacy management.
• Hands-on practical sessions in the laboratory to share experience in drug formulation, analysis, and quality control.
• Supervised and assessed undergraduate and postgraduate students’ presentations, Supervising master's and PhD thesis,
• Assisting with teaching programme development and student assessment.
• Guest Lecturer at the University of Traditional Medicine (2019-2022)

• Asian Federation of Pharmaceutical Science 2015 held in Thailand
• Asian Federation of Pharmaceutical Science 2017 held in China
• Asian Federation of Pharmaceutical Science 2019 held in Indonesia

• Regulatory T cell-targeted hybrid nanoparticles combined with immune checkpoint blockage for cancer immunotherapy, W Ou, RK Thapa, L Jiang, ZC Soe, M Gautam, JH Chang, JH Jeong, Journal of Controlled Release, 281, 84-96, 2018
• Combination of NIR therapy and regulatory T cell modulation using layer-by layer hybrid nanoparticles for effective cancer photoimmunotherapy, W Ou, L Jiang, RK Thapa, ZC Soe, K Poudel, JH Chang, SK Ku, HG Choi, Theranostics, 8, 17, 4574-457, 2018
• Folate receptor-mediated celastrol and irinotecan combination delivery using liposomes for effective chemotherapy, ZC Soe, RK Thapa, W Ou, M Gautam, HT Nguyen, SG Jin, SK Ku, KT Oh, Colloids and Surfaces B: Biointerfaces, 170, 718-728, 2018
• Folate-targeted nanostructured chitosan/chondroitin sulfate complex carriers for enhanced delivery of bortezomib to colorectal cancer cells, ZC Soe, BK Poudel, HT Nguyen, RK Thapa, W Ou, M Gautam, K Poudel, Asian Journal of Pharmaceutical Sciences, 14, 1, 40-51, 2019
• In situ fabrication of mesoporous silica-coated silver-gold hollow nanoshell for remotely controllable chemo-photothermal therapy via phase-change molecule as gatekeepers, BK Poudel, ZC Soe, HB Ruttala, B Gupta, T Ramasamy, RK Thapa, International journal of pharmaceutics, 548, 1, 92-103, 2018
• Transferrin-conjugated polymeric nanoparticle for receptor-mediated delivery of doxorubicin in doxorubicin-resistant breast cancer cells, ZC Soe, JB Kwon, RK Thapa, W Ou, HT Nguyen, M Gautam, KT Oh, Pharmaceutics, 11, 2, 63, 2019
• Palladium nanoparticle-decorated 2-D graphene oxide for effective photodynamic and photothermal therapy of prostate solid tumours, RK Thapa, ZC Soe, W Ou, K Poudel, JH Jeong, SG Jin, SK Ku, HG Choi, Colloids and Surfaces B: Biointerfaces, 169, 429-437, 2018
• Aerosol technique-based carbon-encapsulated hollow mesoporous silica nanoparticles for synergistic chemo-photothermal therapy, M Gautam, RK Thapa, BK Poudel, B Gupta, HB Ruttala, HT Nguyen, Acta biomaterials, 88, 448-461, 2019
• Multifaceted NIR-responsive polymer-peptide-enveloped drug-loaded copper sulfide nano platform for chemo-phototherapy against highly tumorigenic prostate cancer, K Poudel, RK Thapa, M Gautam, W Ou, ZC Soe, B Gupta, HB Ruttala, Nanomedicine: Nanotechnology, Biology and Medicine, 21, 102042, 2019
• Tailored black phosphorus for erythrocyte membrane nano cloaking with interleukin-1α siRNA and paclitaxel for targeted, durable, and mild combination cancer therapy, W Ou, JH Byeon, ZC Soe, BK Kim, RK Thapa, B Gupta, BK Poudel, SK Ku, Theranostics, 9, 23, 6780, 2019
• Transferrin-conjugated pH-sensitive platform for effective delivery of porous palladium nanoparticles and paclitaxel in cancer treatment, HT Nguyen, ZC Soe, KY Yang, C Dai Phung, LTT Nguyen, JH Jeong, Colloids and Surfaces B: Biointerfaces, 176, 265-275, 2019
• Regulatory T cells tailored with pH-responsive liposomes shape an immunoantitumor milieu against tumors, W Ou, L Jiang, Y Gu, ZC Soe, BK Kim, M Gautam, K Poudel, LM Pham, ACS applied materials & interfaces, 11, 40, 36333-36346, 2019
• Phytosterol-loaded CD44 receptor-targeted PEGylated nano-hybrid phytoliposomes for synergistic chemotherapy, M Gautam, RK Thapa, B Gupta, ZC Soe, K Poudel, SG Jin, SK Ku, Expert opinion on drug delivery, 17, 3, 423-434, 2020
• Development of Folate-functionalized PEGylated Zein nanoparticles for ligand-directed delivery of paclitaxel, ZC Soe, W Ou, M Gautam, K Poudel, BK Kim, LM Pham, CD Phung, Pharmaceutics, 11, 11, 562, 2019
• Redox/photo dual-responsive, self-targeted, and photosensitizer-laden bismuth sulfide nanourchins for combination therapy in cancer, K Poudel, A Banstola, M Gautam, ZC Soe, JH Jeong, HG Choi, SK Ku, Nanoscale, 13, 2, 1231-12475, 2021
• Macrophage-membrane-camouflaged disintegrable and excretable nano construct for deep tumor penetration, K Poudel, A Banstola, M Gautam, Z Soe, CD Phung, LM Pham, JH Jeong, ACS Applied Materials & Interfaces, 12, 51, 56767-567815, 2020
• Facile processing for instant production of clinically-approvable nano agents for combination cancer therapy, M Gautam, BK Poudel, ZC Soe, K Poudel, S Maharjan, SK Ku, CS Yong, Chemical Engineering Journal, 383, 123177, 2020
• Stealth polymer-coated graphene oxide decorated mesoporous titania nanoplatforms for in vivo chemo-photodynamic cancer therapy, M Gautam, B Gupta, ZC Soe, K Poudel, S Maharjan, JH Jeong, HG Choi, Pharmaceutical Research, 37, 8, 1-15, 2020
• Receptor-Mediated Delivery of Doxorubicin in Doxorubicin-Resistant Breast Cancer Cells by Using Transferrin-Conjugated Polymeric Nanoparticle, ZC Soe, W Ou, M Gautam, K Poudel, S Maharjan, P Le Minh, CS Yong, Asian Federation for Pharmaceutical Sciences (AFPS), 2019
• Aero-hydro-aero-based scalable on-demand platform to assemble nanocarriers for combination chemophototherapy., S Maharjan, M Gautam, P Le Minh, ZC Soe, CS Yong, JO Kim, Asian Federation for Pharmaceutical Sciences (AFPS), 2019
• Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells, Zar Chi Soe, Zin Zin Ei, Kittichate Visuttijai, Pithi Chanvorachote, Molecules, 28, 14, 5517, 2023

• Chul Soon Yong, Ph.D, Professor, College of Pharmacy, Yeungnam University, 82-53-810-2812, 82-10-9812-2812, csyong@yu.ac.kr
• Jong Oh Kim, Ph.D., Professor, Dean, College of Pharmacy, Yeungnam University, +82-53-810-2813, +82-10-2299-0369, +82-53-810-4654, jongohkim@yu.ac.kr
• Ei Ei Thin, Ph.D, Professor and Head, Department of Pharmaceutical Chemistry, University of Pharmacy, Mandalay, +95-9443046101, eieithin.uopmm@gmail.com

• Workshop on Research Methodology at the Department of Medical Research
• Workshop on Current Good Manufacturing Practice by Korean at the Food and Drug Administration
• Workshop on Medical Education at the University of Medicine II
• Workshop on Total Professional and Personal Development Program (TPPDP)
• Training on chemical safety in Mahidol University, Thailand.